CBD & Manuka Honey Gummies - 25mg CBD & Manuka Honey Gummies - 25mg CBD & Manuka Honey Gummies - 25mg CBD & Manuka Honey Gummies - 25mg CBD & Manuka Honey Gummies - 25mg CBD & Manuka Honey Gummies - 25mg

CBD & Manuka Honey Gummies - 25mg

Please Note: BBE February 2024

High Strength - Lab Pure CBD isolate 25mg per Gummy. 750mg CBD per pot.

Anxiety Relief - Relieves feelings of anxiousness by targeting receptors throughout the nervous system.

Better Sleep - Supports the regulation of sleep chemicals like serotonin by targeting receptors throughout the body. 

Pain Management - Contains powerful anti inflammatory agents to support arthritis relief.

Contains - 30 Gummies 

Global Makeup Awards 2023 - Best CBD Product

Discontinue use and consult a doctor if adverse reactions occur.

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Sale

£7.50 £60.00

You save £52.50

Sale

£7.50 £60.00

You save £52.50

Our High Strength 300 MGO Manuka honey and Lab Pure CBD isolate Gummies are THC-FREE and a tasty way to take your CBD on the go. Gluten-free, non-GMO and with Manuka honey, our Manuka Pharm Gummies are tasty and convenient. Each Manuka honey and CBD Gummy contains 25mg of CBD isolate (30 servings per bottle). They are made with Lab Pure CBD isolate, making them a great option for people who want to avoid THC. We only use natural colours, flavours and sweeteners.

Manuka honey (MGO 300)

This high-strength honey – made by bees collecting nectar from New Zealand Manuka bushes – contains the active ingredient methylglyoxal (MGO), which has an antimicrobial [1] and also anti-bacterial effect on the body, according to a 2018 study by Ulster University. [2] Our Manuka honey is harvested from Manuka Pharm hives high in the New Zealand mountains, and then freeze-dried into powder.

In a 2009 German and New Zealand study, researchers suggested honey could speed up the healing process because: [3]
• honey stimulates the inflammatory response in the body, leading to the regeneration of skin cells and connective tissues
• the pH level of honey is very low, which reduces infection

CBD (Lab Pure CBD Isolate 750mg per pot and 25mg per Gummy)

CBD’s ability to calm is its most well known effect. A 2017 study in the Brazilian Journal of Psychiatry tested the anxiety levels of 57 men in a simulated public speaking test. Those who received 300 milligrams of CBD experienced significantly reduced anxiety during the test compared to those who received the placebo. [4]

Meanwhile, at least one study revealed CBD had effects similar to the antidepressant imipramine. Human trials are needed, though, to confirm whether CBD can induce this same antidepressant reaction in our bodies. [5]

Early research supports the idea that CBD may help with joint pain.  A 2020 study found that CBD has anti-arthritic activity and may help symptoms by targeting the cells that drive inflammation. [6] A 2019 study indicates that CBD helped improve markers of inflammation, pain, and nerve damage in an animal model of osteoarthritis. [7] A 2015 study also found that CBD may reduce pain and inflammation in a rat model of arthritis. [8]

Anecdotal evidence also supports the theory that CBD may help with joint pain. A recent poll from The Arthritis Foundation asked over 2,600 people with arthritis about their experience using CBD. According to their poll, 94% of those who use CBD say they use it to relieve pain. Additionally, 67% of the participants reported improvements in their overall physical functioning from taking CBD. [9]

Cannabidiol (CBD), the non-psychoactive component of Cannabis sativa, is a phytocannabinoid that has proven in research to act on the endocannabinoid system and has the ability to maintain a balanced and healthy immune system.

Transient receptor potential vanilloid 2 (TRPV2), a protein that facilitates the communication of cells with their extracellular environment, plays an important role in healthy immune system function. CBD activates TRPV2 and influences other transient receptor potential (TRP) channels involved in supporting immunity. [10]  

The CBD in Manuka Pharm Gummies is a Lab Pure CBD isolate which is guaranteed to have 0% THC and no other cannabinoids from the cannabis plant. 

Many cannabinoid chemists believe CBD isolates are the safest and most reliable choice of CBD oil, as almost all of the randomised control trials and double blind placebo trials (considered to be the gold standard of testing in the UK) exploring the therapeutic effects of cannabinoids are looking at CBD isolates. So, many cannabinoid chemists and researchers feel we can be most confident about the safety and efficacy of these cannabinoids than any others.

Despite being a single compound, CBD actually has multiple mechanisms via a variety of molecular pathways. Some experts believe these pathways can even change depending on the need of the body. This, and the fact that CBD is biphasic (has different effects at different doses) means just this molecule all by itself can provide a wide ranges of wellbeing benefits.

 Each batch of Manuka Pharm Pure Lab CBD isolate is independently tested and certified and is fully traceable from seed to shelf.

  1. Alvarez-Suarez JM, et al. The Composition and Biological Activity of Honey: A Focus on Manuka Honey. Foods. 2014 Sep;3(3):420-432. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5302252/
  2. Johnston M, et al. Antibacterial activity of Manuka honey and its components: An overview. AIMS Microbiology. 2018. 4(4):665-664. https://www.aimspress.com/fileOther/PDF/microbiology/microbiol-04-04-655.pdf
  3. Simon A, et al. Medical Honey for Wound Care – Still the ‘Latest Resort’? Evid Based Complement Alternat Med. 2009 Jun; 6(2): 165–173.
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2686636/
  4. Linares IM, Zuardi AW, Pereira LC, et al. Cannabidiol presents an inverted U-shaped dose-response curve in a simulated public speaking testRevista brasileira de psiquiatria.2019;41(1):9-14.
  5. Zanelati TV, Biojone C, Moreira FA, Guimarães FS, Joca SR. Antidepressant-like effects of cannabidiol in mice: possible involvement of 5-HT1A receptorsBr J Pharmacol. 2010;159(1):122-128.
  6. Torsten Lowin, et al. Cannabidiol (CBD): a killer for inflammatory rheumatoid arthritis synovial fibroblasts. Cell Death & Disease. 2020 Aug; 11(8): 714.
  7. Holly T Philpott et al. Attenuation of early phase inflammation by cannabidiol prevents pain and nerve damage in rat osteoarthritis. Pain. 2017 Dec; 158(12): 2442–2451.
  8. DC Hammell et al. Transdermal cannabidiol reduces inflammation and pain-related behaviours in a rat model of arthritis. Eur j Pain. 2016 Jul; 20(6): 936-948.
  9. http://blog.arthritis.org/news/patients-tell-us-cbd-use/
  10. Pumroy RA, Samanta A, Liu Y, et al. Molecular mechanism of TRPV2 channel modulation by cannabidiol. Elife. 2019 Sep 30;8. pii: e48792.

Take at any time of day but do not exceed 2 Gummies per day. 1 Gummy = 25mg, 2 Gummies = 50mg

Discontinue use and consult a doctor if adverse reactions occur. Avoid this product if you have allergies to pollen, bees or bee products. Do not use this product without first consulting with your doctor if you are under medical supervision, on prescribed medication, pregnant, breastfeeding, have asthma or related allergies. Keep out of reach of children. Food supplements should not be used as a substitute for a varied diet. Store in a cool and dry place. Allergens: None 

 

Organic Sugar, Manuka Honey, Organic Tapioca Syrup, Organic Pear Juice Concentrate, Organic Tapioca Maltodextrin, Pectin, Citric Acid, Natural Flavour, Cannabidiol Isolate, Sodium Citrate, and Steviol Glycosides. 

UK Mainland Delivery Rates

All orders FREE Royal Mail 2nd Class (5-7 working days) Signed for delivery

 

Calculation of Shipping Costs

Shipping costs are based on the grand total of your order. If you apply a discount code or loyalty credit your total may change and shipping costs will be recalculated.

Failed Deliveries

If the delivery of your order cannot be completed and it is returned to our warehouse we will contact you to offer two options for your order:

(i) We will re-arrange delivery of your order but you will be required to pay a £3.50 resend fee before the parcel is resent.

(ii) We will refund your order less the £6.50 shipping fee that we are charged by DPD.

Please see clause 8 of the Terms and Conditions of Supply for more information.

Returns

1. If you change your mind and don’t want the Product within 14 days of its delivery to you, your rights to cancel are set out at clause 11 of our Terms and Conditions of Supply. Please note to be eligible for a refund the Product must be unopened, in its original packaging and sealed. We will only be obliged to process any refund due once we have received the Product back from you.

If you are returning your order because you have changed your mind then:
You are responsible for the cost of return postage of the items.

2. If you discover that the Product is faulty or not of satisfactory quality within 30 days of the Product being delivered or us delivering the Product you may also be entitled to a refund or exchange in accordance with clause 11.9 of our Terms and Conditions of Supply.

3. Ensure that if you do want to cancel a contract you follow the cancellation procedure at clause 11 of the Terms and Conditions of Supply. Failure to do so may result in a delay in any refund being processed.

4. We strive to ensure all our Products are of the highest standard. If you do feel there is something wrong with the Product or if you have any questions please feel free to email us on customerservices@manukapharm.co.uk

Description

Our High Strength 300 MGO Manuka honey and Lab Pure CBD isolate Gummies are THC-FREE and a tasty way to take your CBD on the go. Gluten-free, non-GMO and with Manuka honey, our Manuka Pharm Gummies are tasty and convenient. Each Manuka honey and CBD Gummy contains 25mg of CBD isolate (30 servings per bottle). They are made with Lab Pure CBD isolate, making them a great option for people who want to avoid THC. We only use natural colours, flavours and sweeteners.

Why it works

Manuka honey (MGO 300)

This high-strength honey – made by bees collecting nectar from New Zealand Manuka bushes – contains the active ingredient methylglyoxal (MGO), which has an antimicrobial [1] and also anti-bacterial effect on the body, according to a 2018 study by Ulster University. [2] Our Manuka honey is harvested from Manuka Pharm hives high in the New Zealand mountains, and then freeze-dried into powder.

In a 2009 German and New Zealand study, researchers suggested honey could speed up the healing process because: [3]
• honey stimulates the inflammatory response in the body, leading to the regeneration of skin cells and connective tissues
• the pH level of honey is very low, which reduces infection

CBD (Lab Pure CBD Isolate 750mg per pot and 25mg per Gummy)

CBD’s ability to calm is its most well known effect. A 2017 study in the Brazilian Journal of Psychiatry tested the anxiety levels of 57 men in a simulated public speaking test. Those who received 300 milligrams of CBD experienced significantly reduced anxiety during the test compared to those who received the placebo. [4]

Meanwhile, at least one study revealed CBD had effects similar to the antidepressant imipramine. Human trials are needed, though, to confirm whether CBD can induce this same antidepressant reaction in our bodies. [5]

Early research supports the idea that CBD may help with joint pain.  A 2020 study found that CBD has anti-arthritic activity and may help symptoms by targeting the cells that drive inflammation. [6] A 2019 study indicates that CBD helped improve markers of inflammation, pain, and nerve damage in an animal model of osteoarthritis. [7] A 2015 study also found that CBD may reduce pain and inflammation in a rat model of arthritis. [8]

Anecdotal evidence also supports the theory that CBD may help with joint pain. A recent poll from The Arthritis Foundation asked over 2,600 people with arthritis about their experience using CBD. According to their poll, 94% of those who use CBD say they use it to relieve pain. Additionally, 67% of the participants reported improvements in their overall physical functioning from taking CBD. [9]

Cannabidiol (CBD), the non-psychoactive component of Cannabis sativa, is a phytocannabinoid that has proven in research to act on the endocannabinoid system and has the ability to maintain a balanced and healthy immune system.

Transient receptor potential vanilloid 2 (TRPV2), a protein that facilitates the communication of cells with their extracellular environment, plays an important role in healthy immune system function. CBD activates TRPV2 and influences other transient receptor potential (TRP) channels involved in supporting immunity. [10]  

The CBD in Manuka Pharm Gummies is a Lab Pure CBD isolate which is guaranteed to have 0% THC and no other cannabinoids from the cannabis plant. 

Many cannabinoid chemists believe CBD isolates are the safest and most reliable choice of CBD oil, as almost all of the randomised control trials and double blind placebo trials (considered to be the gold standard of testing in the UK) exploring the therapeutic effects of cannabinoids are looking at CBD isolates. So, many cannabinoid chemists and researchers feel we can be most confident about the safety and efficacy of these cannabinoids than any others.

Despite being a single compound, CBD actually has multiple mechanisms via a variety of molecular pathways. Some experts believe these pathways can even change depending on the need of the body. This, and the fact that CBD is biphasic (has different effects at different doses) means just this molecule all by itself can provide a wide ranges of wellbeing benefits.

 Each batch of Manuka Pharm Pure Lab CBD isolate is independently tested and certified and is fully traceable from seed to shelf.

  1. Alvarez-Suarez JM, et al. The Composition and Biological Activity of Honey: A Focus on Manuka Honey. Foods. 2014 Sep;3(3):420-432. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5302252/
  2. Johnston M, et al. Antibacterial activity of Manuka honey and its components: An overview. AIMS Microbiology. 2018. 4(4):665-664. https://www.aimspress.com/fileOther/PDF/microbiology/microbiol-04-04-655.pdf
  3. Simon A, et al. Medical Honey for Wound Care – Still the ‘Latest Resort’? Evid Based Complement Alternat Med. 2009 Jun; 6(2): 165–173.
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2686636/
  4. Linares IM, Zuardi AW, Pereira LC, et al. Cannabidiol presents an inverted U-shaped dose-response curve in a simulated public speaking testRevista brasileira de psiquiatria.2019;41(1):9-14.
  5. Zanelati TV, Biojone C, Moreira FA, Guimarães FS, Joca SR. Antidepressant-like effects of cannabidiol in mice: possible involvement of 5-HT1A receptorsBr J Pharmacol. 2010;159(1):122-128.
  6. Torsten Lowin, et al. Cannabidiol (CBD): a killer for inflammatory rheumatoid arthritis synovial fibroblasts. Cell Death & Disease. 2020 Aug; 11(8): 714.
  7. Holly T Philpott et al. Attenuation of early phase inflammation by cannabidiol prevents pain and nerve damage in rat osteoarthritis. Pain. 2017 Dec; 158(12): 2442–2451.
  8. DC Hammell et al. Transdermal cannabidiol reduces inflammation and pain-related behaviours in a rat model of arthritis. Eur j Pain. 2016 Jul; 20(6): 936-948.
  9. http://blog.arthritis.org/news/patients-tell-us-cbd-use/
  10. Pumroy RA, Samanta A, Liu Y, et al. Molecular mechanism of TRPV2 channel modulation by cannabidiol. Elife. 2019 Sep 30;8. pii: e48792.
Directions & Warnings

Take at any time of day but do not exceed 2 Gummies per day. 1 Gummy = 25mg, 2 Gummies = 50mg

Discontinue use and consult a doctor if adverse reactions occur. Avoid this product if you have allergies to pollen, bees or bee products. Do not use this product without first consulting with your doctor if you are under medical supervision, on prescribed medication, pregnant, breastfeeding, have asthma or related allergies. Keep out of reach of children. Food supplements should not be used as a substitute for a varied diet. Store in a cool and dry place. Allergens: None 

 

Ingredients

Organic Sugar, Manuka Honey, Organic Tapioca Syrup, Organic Pear Juice Concentrate, Organic Tapioca Maltodextrin, Pectin, Citric Acid, Natural Flavour, Cannabidiol Isolate, Sodium Citrate, and Steviol Glycosides. 

Delivery & Returns

UK Mainland Delivery Rates

All orders FREE Royal Mail 2nd Class (5-7 working days) Signed for delivery

 

Calculation of Shipping Costs

Shipping costs are based on the grand total of your order. If you apply a discount code or loyalty credit your total may change and shipping costs will be recalculated.

Failed Deliveries

If the delivery of your order cannot be completed and it is returned to our warehouse we will contact you to offer two options for your order:

(i) We will re-arrange delivery of your order but you will be required to pay a £3.50 resend fee before the parcel is resent.

(ii) We will refund your order less the £6.50 shipping fee that we are charged by DPD.

Please see clause 8 of the Terms and Conditions of Supply for more information.

Returns

1. If you change your mind and don’t want the Product within 14 days of its delivery to you, your rights to cancel are set out at clause 11 of our Terms and Conditions of Supply. Please note to be eligible for a refund the Product must be unopened, in its original packaging and sealed. We will only be obliged to process any refund due once we have received the Product back from you.

If you are returning your order because you have changed your mind then:
You are responsible for the cost of return postage of the items.

2. If you discover that the Product is faulty or not of satisfactory quality within 30 days of the Product being delivered or us delivering the Product you may also be entitled to a refund or exchange in accordance with clause 11.9 of our Terms and Conditions of Supply.

3. Ensure that if you do want to cancel a contract you follow the cancellation procedure at clause 11 of the Terms and Conditions of Supply. Failure to do so may result in a delay in any refund being processed.

4. We strive to ensure all our Products are of the highest standard. If you do feel there is something wrong with the Product or if you have any questions please feel free to email us on customerservices@manukapharm.co.uk

All reviews of the Products submitted onto the Site by customers are solely the unbiased, independent opinions expressed by our customers following purchase and use of the Products. For further information click here.